BioCure's Bone Cement

BioCure is developing a series of novel bone void fillers and bone cements for both non-load bearing and load bearing applications based upon its polyvinyl alcohol (PVA) hydrogel technology platform. The load bearing bone cement is being developed for the augmentation of vertebral compression fractures and is compatible with current vertebroplasty and kyphoplasty procedures. This novel non-PMMA-based bone cement provides significant advantages over PMMA and calcium salt filler products currently on the market. The unique characteristics of BioCure's bone cement(s) include: (1) formulations with predefined mechanical properties to match those of different cancellous bone designed to reduce subsequent vertebral fracture, especially adjacent vertebral fracture; (2) low exotherm preventing tissue necrosis; (3) reaching designed or ultimate mechanical properties soon after the injection of cement for reduced recovery time; (4) better interdigitation with adjacent tissue and better bone cement injection pattern; (5) delivery through a small gauge needles (e.g. 18G, 4"-8" long needles) for a minimally invasive, outpatient procedure with minimum sedation; and finally (6) a biocompatible and cohesive product.

A poster containing a summary of results is available for download. Also, the following paper, entitled "A New Concept for More Biocompliant Bone Cements for Vertebroplasty and Kyphoplasty" was published in Macromolecular Biosciences 2009, 9, 195-202.

BioCure is actively seeking licensing and/or collaborative development opportunities for this product.

Please contact us if you have any questions. We'd be happy to provide you with more information.